7DTC

voltage-gated sodium channel Nav1.5-E1784K

Summary for 7DTC

• Entry DOI: 10.2210/pdb7dtc/pdb
• EMDB information: 30850
• Descriptor: Sodium channel protein type 5 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: voltage-gated sodium channel, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 233734.87

Authors

Yan, N.,Pan, X.,Li, Z. (deposition date: 2021-01-04, release date: 2021-03-24)

• Primary citation: Li, Z.,Jin, X.,Wu, T.,Zhao, X.,Wang, W.,Lei, J.,Pan, X.,Yan, N.; Structure of human Na v 1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33712541; DOI: 10.1073/pnas.2100069118

Experimental method

ELECTRON MICROSCOPY (3.3 Å)