7ATU

The LIMK1 Kinase Domain Bound To LIJTF500025

Summary for 7ATU

• Entry DOI: 10.2210/pdb7atu/pdb
• Descriptor: LIM domain kinase 1, (S)-2-benzyl-6-(8-chloro-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-7-oxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide (3 entities in total)
• Functional Keywords: kinase inhibitor cfl1 actin cytoskeleton, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 145898.76

Authors

Mathea, S.,Chatterjee, D.,Preuss, F.,Yamamoto, S.,Tawada, M.,Nomura, I.,Takagi, T.,Ahmed, M.,Little, W.,Mueller-Knapp, S.,Knapp, S. (deposition date: 2020-10-30, release date: 2020-12-23, Last modification date: 2024-01-31)

• Primary citation: Mathea, S.,Chatterjee, D.,Preuss, F.,Yamamoto, S.,Tawada, M.,Nomura, I.,Takagi, T.,Ahmed, M.,Little, W.,Mueller-Knapp, S.,Knapp, S.; The LIMK1 Kinase Domain Bound To LIJTF500025; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)