7AQX
Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB9)
Summary for 7AQX
Entry DOI | 10.2210/pdb7aqx/pdb |
Descriptor | Variant surface glycoprotein MITAT 1.2, Nanobody VSG2(NB9), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | variant surface glycoprotein, epitope mapping, immune evasion, membrane protein |
Biological source | Lama glama (Llama) More |
Total number of polymer chains | 4 |
Total formula weight | 110706.69 |
Authors | Stebbins, C.E.,Hempelmann, A. (deposition date: 2020-10-23, release date: 2021-11-03, Last modification date: 2024-02-07) |
Primary citation | Hempelmann, A.,Hartleb, L.,van Straaten, M.,Hashemi, H.,Zeelen, J.P.,Bongers, K.,Papavasiliou, F.N.,Engstler, M.,Stebbins, C.E.,Jones, N.G. Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37:109923-109923, 2021 Cited by PubMed: 34731611DOI: 10.1016/j.celrep.2021.109923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.499 Å) |
Structure validation
Download full validation report