7AKR
Human ADP-ribosylserine hydrolase ARH3 mutant E41A in complex with ADP-ribose dimer
This is a non-PDB format compatible entry.
Summary for 7AKR
Entry DOI | 10.2210/pdb7akr/pdb |
Descriptor | ADP-ribose glycohydrolase ARH3, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (6 entities in total) |
Functional Keywords | adp-ribosylation, adp-ribose, adprhl2, adp-ribosylhydrolase like 2, ser-adpr, serine-adpr, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 157042.15 |
Authors | Ariza, A. (deposition date: 2020-10-02, release date: 2021-06-16, Last modification date: 2024-01-31) |
Primary citation | Rack, J.G.M.,Liu, Q.,Zorzini, V.,Voorneveld, J.,Ariza, A.,Honarmand Ebrahimi, K.,Reber, J.M.,Krassnig, S.C.,Ahel, D.,van der Marel, G.A.,Mangerich, A.,McCullagh, J.S.O.,Filippov, D.V.,Ahel, I. Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nat Commun, 12:4581-4581, 2021 Cited by PubMed: 34321462DOI: 10.1038/s41467-021-24723-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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