7AG5
Structure of the Laspartomycin C double mutant G4D D-allo-Thr9D-Dap in complex with Geranyl phosphate
Summary for 7AG5
Entry DOI | 10.2210/pdb7ag5/pdb |
Descriptor | Laspartomycin C double mutant G4D D-allo-Thr9D-Dap, CALCIUM ION, Geranyl phosphate, ... (5 entities in total) |
Functional Keywords | antibiotic, calcium-dependent antibiotic, bacterial cell wall biosynthesis inhibitor, lipopeptide antibiotic |
Biological source | Streptomyces viridochromogenes |
Total number of polymer chains | 1 |
Total formula weight | 1641.85 |
Authors | Zeronian, M.R.,Pearce, N.M.,Wood, T.M.,Martin, N.I.,Janssen, B.J.C. (deposition date: 2020-09-21, release date: 2022-02-02, Last modification date: 2024-01-31) |
Primary citation | Wood, T.M.,Zeronian, M.R.,Buijs, N.,Bertheussen, K.,Abedian, H.K.,Johnson, A.V.,Pearce, N.M.,Lutz, M.,Kemmink, J.,Seirsma, T.,Hamoen, L.W.,Janssen, B.J.C.,Martin, N.I. Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Chem Sci, 13:2985-2991, 2022 Cited by DOI: 10.1039/D1SC07190DPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.04 Å) |
Structure validation
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