7A3K
Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1
Summary for 7A3K
Entry DOI | 10.2210/pdb7a3k/pdb |
Related | 6EOP |
Descriptor | Dipeptidyl peptidase 8, trimethylamine oxide, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | dpp8, protease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 312271.00 |
Authors | Ross, B.H.,Huber, R. (deposition date: 2020-08-18, release date: 2021-07-07, Last modification date: 2024-01-31) |
Primary citation | Fehr, L.,Carvalho, L.A.R.,Ross, B.H.,Lum, K.,Vieira, A.C.,Kiefersauer, R.,Geiss-Friedlander, R.,Kaiser, M.,Rodrigues, T.,Lucas, S.D.,Cravatt, B.F.,Huber, R.,Moreira, R. Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9 To Be Published, |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)