7A0P
Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11i
Summary for 7A0P
Entry DOI | 10.2210/pdb7a0p/pdb |
Related | 6YKK 6YKL 6YKN 6YKQ 6YKS 6YKT 6YKU 6YKV 6YKW 6YKX |
Descriptor | Leucine--tRNA ligase, 1,2-ETHANEDIOL, ZINC ION, ... (6 entities in total) |
Functional Keywords | protein-inhibitor complex, rossmann fold, trna synthetase, ligase |
Biological source | Neisseria gonorrhoeae |
Total number of polymer chains | 1 |
Total formula weight | 99043.93 |
Authors | Pang, L.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2020-08-10, release date: 2020-12-02, Last modification date: 2024-01-31) |
Primary citation | De Ruysscher, D.,Pang, L.,Lenders, S.M.G.,Cappoen, D.,Cos, P.,Rozenski, J.,Strelkov, S.V.,Weeks, S.D.,Van Aerschot, A. Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211:113021-113021, 2021 Cited by PubMed: 33248851DOI: 10.1016/j.ejmech.2020.113021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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