6ZZP

Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Psychrobacter arcticus complexed with NAD+ and 3-oxovalerate

Summary for 6ZZP

Entry DOI	10.2210/pdb6zzp/pdb
Related	6ZZO
Descriptor	Putative beta-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-oxidanylidenepentanoic acid, ... (4 entities in total)
Functional Keywords	(r)-3-hydroxybutyrate dehydrogenase, psychrophilic enzyme, short-chain dehydrogenase/reductase, oxidoreductase
Biological source	Psychrobacter arcticus
Total number of polymer chains	4
Total formula weight	115971.57
Authors	Machado, T.F.G.,da Silva, R.G.,Gloster, T.M.,McMahon, S.A.,Oehler, V. (deposition date: 2020-08-04, release date: 2020-10-07, Last modification date: 2021-01-20)
Primary citation	Machado, T.F.G.,Purg, M.,McMahon, S.A.,Read, B.J.,Oehler, V.,Aqvist, J.,Gloster, T.M.,da Silva, R.G. Dissecting the Mechanism of ( R )-3-Hydroxybutyrate Dehydrogenase by Kinetic Isotope Effects, Protein Crystallography, and Computational Chemistry. Acs Catalysis, 10:15019-15032, 2020 Cited by PubMed: 33391858 DOI: 10.1021/acscatal.0c04736 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation