6ZRE
Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
Summary for 6ZRE
Entry DOI | 10.2210/pdb6zre/pdb |
Descriptor | Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | efflux pump, antibiotic resistance, tolc-like, outer-membrane channel., translocase |
Biological source | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Total number of polymer chains | 2 |
Total formula weight | 106663.43 |
Authors | Ntsogo Enguene, Y.V.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I. (deposition date: 2020-07-13, release date: 2021-07-28, Last modification date: 2024-01-31) |
Primary citation | Ntsogo Enguene, Y.V.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I. Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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