6ZR9
The crystal structure of the complex of hCAVII with 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide
Summary for 6ZR9
Entry DOI | 10.2210/pdb6zr9/pdb |
Descriptor | Carbonic anhydrase 7, ZINC ION, 2-[4-(diphenylmethyl)piperazin-1-yl]-~{N}-(4-sulfamoylphenyl)ethanamide, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase vii, protein-inhibitor complex, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31455.68 |
Authors | |
Primary citation | D'Ambrosio, K.,Di Fiore, A.,Buonanno, M.,Kumari, S.,Tiwari, M.,Supuran, C.T.,Mishra, C.B.,Monti, S.M.,De Simone, G. The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development New J.Chem., 45:147-152, 2021 Cited by DOI: 10.1039/D0NJ03544KPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report