6ZQT

Crystal structure of the RLIP76 Ral binding domain mutant (E427H/Q433L/K440R) in complex with RalB-GMPPNP

6ZQT の概要

• エントリーDOI: 10.2210/pdb6zqt/pdb
• 分子名称: Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
• 機能のキーワード: ralb, rlip76, ral binding domain, coiled-coil, small gtpase, g protein, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56962.41

構造登録者

Hurd, C.,Brear, P.,Revell, J.,Ross, S.,Mott, H.,Owen, D. (登録日: 2020-07-10, 公開日: 2020-11-25, 最終更新日: 2024-01-31)

• 主引用文献: Hurd, C.A.,Brear, P.,Revell, J.,Ross, S.,Mott, H.R.,Owen, D.; Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.; J.Biol.Chem., 296:100101-100101, 2020; PubMed: 33214225; DOI: 10.1074/jbc.RA120.015735

実験手法

X-RAY DIFFRACTION (1.51 Å)