6ZOK
SARS-CoV-2-Nsp1-40S complex, focused on body
Summary for 6ZOK
Entry DOI | 10.2210/pdb6zok/pdb |
EMDB information | 11321 |
Descriptor | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... (24 entities in total) |
Functional Keywords | inhibitor, mrna channel, 40s ribosomal subunit, translation |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 22 |
Total formula weight | 1000221.22 |
Authors | Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.-A.,Leibundgut, M.,Thiel, V.,Muehlemann, O.,Ban, N. (deposition date: 2020-07-07, release date: 2020-07-29, Last modification date: 2021-02-10) |
Primary citation | Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.A.,Leibundgut, M.,Thiel, V.,Muhlemann, O.,Ban, N. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27:959-966, 2020 Cited by PubMed: 32908316DOI: 10.1038/s41594-020-0511-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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