6ZN6
Protein polybromo-1 (PB1 BD2) Bound To MW278
Summary for 6ZN6
Entry DOI | 10.2210/pdb6zn6/pdb |
Descriptor | Protein polybromo-1, 2-[6-azanyl-5-[(3~{R})-3-phenoxypiperidin-1-yl]pyridazin-3-yl]phenol, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | bromodomain inhibitor epigenetics, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 27249.52 |
Authors | Preuss, F.,Mathea, S.,Chatterjee, D.,Wanior, M.,Joerger, A.C.,Knapp, S. (deposition date: 2020-07-06, release date: 2020-08-26, Last modification date: 2024-01-31) |
Primary citation | Wanior, M.,Preuss, F.,Ni, X.,Kramer, A.,Mathea, S.,Gobel, T.,Heidenreich, D.,Simonyi, S.,Kahnt, A.S.,Joerger, A.C.,Knapp, S. Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J.Med.Chem., 63:14680-14699, 2020 Cited by PubMed: 33216538DOI: 10.1021/acs.jmedchem.0c01242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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