6ZMD

Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP

6ZMD の概要

• エントリーDOI: 10.2210/pdb6zmd/pdb
• 分子名称: Endoplasmic reticulum chaperone BiP, Protein adenylyltransferase FICD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (7 entities in total)
• 機能のキーワード: ampylation, endoplasmic reticulum, fic enzyme, chaperone, post-translational modification, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98330.51

構造登録者

Fauser, J.,Gulen, B.,Pett, C.,Hedberg, C.,Itzen, A.,Pogenberg, V. (登録日: 2020-07-02, 公開日: 2021-04-14, 最終更新日: 2024-01-31)

• 主引用文献: Fauser, J.,Gulen, B.,Pogenberg, V.,Pett, C.,Pourjafar-Dehkordi, D.,Krisp, C.,Hopfner, D.,Konig, G.,Schluter, H.,Feige, M.J.,Zacharias, M.,Hedberg, C.,Itzen, A.; Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD.; Nat Commun, 12:2426-2426, 2021; PubMed: 33893288; DOI: 10.1038/s41467-021-22596-0

実験手法

X-RAY DIFFRACTION (2.64 Å)