6ZJE
Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Ap5A
Summary for 6ZJE
Entry DOI | 10.2210/pdb6zje/pdb |
Descriptor | GTP:AMP phosphotransferase AK3, mitochondrial, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | gtp:amp phosphotransferase, ap5a, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 26633.96 |
Authors | Grundstrom, C.,Rogne, P.,Wolf-Watz, M.,Sauer-Eriksson, A.E. (deposition date: 2020-06-28, release date: 2020-09-16, Last modification date: 2024-01-31) |
Primary citation | Rogne, P.,Dulko-Smith, B.,Goodman, J.,Rosselin, M.,Grundstrom, C.,Hedberg, C.,Nam, K.,Sauer-Eriksson, A.E.,Wolf-Watz, M. Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59:3570-3581, 2020 Cited by PubMed: 32822537DOI: 10.1021/acs.biochem.0c00549 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
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