6ZIO

CRYSTAL STRUCTURE OF NRAS (C118S) IN COMPLEX WITH GDP

Summary for 6ZIO

• Entry DOI: 10.2210/pdb6zio/pdb
• Descriptor: GTPase NRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: gtpase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 40183.75

Authors

Kessler, D.,Fischer, G.,Boettcher, J. (deposition date: 2020-06-26, release date: 2020-08-19, Last modification date: 2024-01-31)

• Primary citation: Kessler, D.,Bergner, A.,Bottcher, J.,Fischer, G.,Dobel, S.,Hinkel, M.,Mullauer, B.,Weiss-Puxbaum, A.,McConnell, D.B.; Drugging all RAS isoforms with one pocket.; Future Med Chem, 12:1911-1923, 2020; PubMed: 32779487; DOI: 10.4155/fmc-2020-0221

Experimental method

X-RAY DIFFRACTION (1.55 Å)