6ZFC

Fucose-binding lectin from Burkholderia ambifaria (BamBL) in complex with a fucosyl derivative

Summary for 6ZFC

• Entry DOI: 10.2210/pdb6zfc/pdb
• Descriptor: bacterial lectin from Burkholderia ambifaria, 2-[(2~{S},3~{S},4~{R},4~{a}~{S},10~{a}~{S})-2-methyl-3,4-bis(oxidanyl)-3,4,4~{a},10~{a}-tetrahydro-2~{H}-pyrano[2,3-b][1,4]benzoxathiin-7-yl]-~{N}-(3-oxidanylpropyl)ethanamide (3 entities in total)
• Functional Keywords: fucose-binding lectin, glycomimetics, sugar binding protein
• Biological source: Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)
• Total number of polymer chains: 6
• Total formula weight: 60756.19

Authors

Kuhaudomlarp, S.,Gillon, E.,Fragai, M.,Cerofolini, L.,Giuntini, S.,Denis, M.,Santarsia, S.,Valori, C.,Dondoni, A.,Fallarini, S.,Lombardi, G.,Nativi, C.,Imberty, A. (deposition date: 2020-06-17, release date: 2020-10-28, Last modification date: 2024-01-24)

• Primary citation: Kuhaudomlarp, S.,Cerofolini, L.,Santarsia, S.,Gillon, E.,Fallarini, S.,Lombardi, G.,Denis, M.,Giuntini, S.,Valori, C.,Fragai, M.,Imberty, A.,Dondoni, A.,Nativi, C.; Fucosylated ubiquitin and orthogonally glycosylated mutant A28C: conceptually new ligands for Burkholderia ambifaria lectin (BambL).; Chem Sci, 11:12662-12670, 2020; PubMed: 34094460; DOI: 10.1039/d0sc03741a

Experimental method

X-RAY DIFFRACTION (1.65 Å)