6ZCY

SYK Kinase domain in complex with diamine inhibitor 16

Summary for 6ZCY

• Entry DOI: 10.2210/pdb6zcy/pdb
• Descriptor: Tyrosine-protein kinase SYK, ~{N},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{R})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide (3 entities in total)
• Functional Keywords: syk kinase transferase inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 35327.48

Authors

Read, J.A. (deposition date: 2020-06-12, release date: 2021-06-23, Last modification date: 2024-01-24)

• Primary citation: Read, J.A.; SYK Kinase domain in complex with azabenzimidazole inhibitor 16; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.81 Å)