6ZBX

Structure of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6- alpha-manno-cyclophellitol carbasugar-stabilised trisaccharide inhibitor

Summary for 6ZBX

Entry DOI	10.2210/pdb6zbx/pdb
Descriptor	Alpha-1,6-mannanase, UNK-UNK-UNK-UNK, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	mannanase, cyclophellitol, epoxide, hydrolase
Biological source	Bacillus circulans More
Total number of polymer chains	3
Total formula weight	83449.33
Authors	Schroeder, S.,Offen, W.A.,Jin, Y.,De Boer, C.,Enoterpi, J.,Marino, L.,van der Marel, G.A.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2020-06-09, release date: 2021-04-28, Last modification date: 2024-01-24)
Primary citation	Schroder, S.P.,Offen, W.A.,Males, A.,Jin, Y.,de Boer, C.,Enotarpi, J.,Marino, L.,van der Marel, G.A.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Davies, G.J. Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27:9519-9523, 2021 Cited by PubMed: 33878235 DOI: 10.1002/chem.202101255 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation