6Z7V
Crystal structure of Mindy2 (C266A) in complex with Lys48 linked di-ubiquitin (K48-Ub2)
Summary for 6Z7V
Entry DOI | 10.2210/pdb6z7v/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase MINDY-2, Polyubiquitin-C, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, cysteine protease, isopeptidase and ubiquitin binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 123113.67 |
Authors | Abdul Rehman, S.A.,Lange, S.M.,Kulathu, Y. (deposition date: 2020-06-01, release date: 2021-06-09, Last modification date: 2024-01-24) |
Primary citation | Abdul Rehman, S.A.,Armstrong, L.A.,Lange, S.M.,Kristariyanto, Y.A.,Grawert, T.W.,Knebel, A.,Svergun, D.I.,Kulathu, Y. Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81:4176-4190.e6, 2021 Cited by PubMed: 34529927DOI: 10.1016/j.molcel.2021.08.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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