6Z7A

Variant Surface Glycoprotein VSGsur

6Z7A の概要

• エントリーDOI: 10.2210/pdb6z7a/pdb
• 分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein
• 由来する生物種: Trypanosoma brucei rhodesiense
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53541.05

構造登録者

Zeelen, J.P.,Straaten van, M.,Stebbins, C.E.,Hashemi, H. (登録日: 2020-05-30, 公開日: 2021-05-26, 最終更新日: 2024-01-24)

• 主引用文献: Zeelen, J.P.,van Straaten, M.,Verdi, J.,Hempelmann, A.,Hashemi, H.,Perez, K.,Jeffrey, P.D.,Haelg, S.,Wiedemar, N.,Maeser, P.,Papavasiliou, F.N.,Stebbins, C.E.; A Parasite Coat Protein Binds Suramin to Confer Drug Resistance; Nat Microbiol, 6:392-400, 2021; DOI: 10.1038/s41564-020-00844-1

実験手法

X-RAY DIFFRACTION (1.21 Å)