6Z6I
SARS-CoV-2 Macrodomain in complex with ADP-HPD
Summary for 6Z6I
Entry DOI | 10.2210/pdb6z6i/pdb |
Descriptor | Replicase polyprotein 1ab, 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | viral macrodomain, adp-ribose binding module, adp-ribosylhydrolase, adp-ribosylation, viral protein, adp-hpd |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 4 |
Total formula weight | 80852.05 |
Authors | Zorzini, V.,Rack, J.,Ahel, I. (deposition date: 2020-05-28, release date: 2020-12-02, Last modification date: 2024-01-24) |
Primary citation | Rack, J.G.M.,Zorzini, V.,Zhu, Z.,Schuller, M.,Ahel, D.,Ahel, I. Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential. Open Biology, 10:200237-200237, 2020 Cited by PubMed: 33202171DOI: 10.1098/rsob.200237 PDB entries with the same primary citation |
Experimental method |
Structure validation
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