6Z57

Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078

6Z57 の概要

• エントリーDOI: 10.2210/pdb6z57/pdb
• 分子名称: Serine/threonine-protein kinase haspin, 10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41573.61

構造登録者

Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2020-05-26, 公開日: 2020-06-03, 最終更新日: 2024-01-24)

• 主引用文献: Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004078; To Be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)