6Z4A
Structure of the human SAS-6 N-terminal domain, F131E mutant
Summary for 6Z4A
Entry DOI | 10.2210/pdb6z4a/pdb |
Descriptor | Spindle assembly abnormal protein 6 homolog, GLYCEROL (3 entities in total) |
Functional Keywords | centrosome, centriole, cartwheel, alpha/beta protein, structural protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 17837.63 |
Authors | Busch, J.M.C.,Vakonakis, I. (deposition date: 2020-05-25, release date: 2020-09-09, Last modification date: 2024-02-07) |
Primary citation | Busch, J.M.C.,Matsoukas, M.T.,Musgaard, M.,Spyroulias, G.A.,Biggin, P.C.,Vakonakis, I. Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization. J.Biol.Chem., 295:17922-17934, 2020 Cited by PubMed: 32873708DOI: 10.1074/jbc.RA120.014780 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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