6Z36
Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118
Summary for 6Z36
Entry DOI | 10.2210/pdb6z36/pdb |
Descriptor | Activin receptor type I, SULFATE ION, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | kinase, inhibitor complex, receptor, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 71714.08 |
Authors | Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (deposition date: 2020-05-19, release date: 2020-05-27, Last modification date: 2024-01-24) |
Primary citation | Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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