6Z2J

The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex

6Z2J の概要

• エントリーDOI: 10.2210/pdb6z2j/pdb
• EMDBエントリー: 11041
• 分子名称: Histone deacetylase 1, Deoxynucleotidyltransferase terminal-interacting protein 1, Mitotic deacetylase-associated SANT domain protein, ... (6 entities in total)
• 機能のキーワード: hdac1 mideas elmsan1 dnttip1 tdif1 histone deacetylase midac, gene regulation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 180317.22

構造登録者

Fairall, L.,Saleh, A.,Ragan, T.J.,Millard, C.J.,Savva, C.G.,Schwabe, J.W.R. (登録日: 2020-05-16, 公開日: 2020-07-08, 最終更新日: 2024-05-22)

• 主引用文献: Turnbull, R.E.,Fairall, L.,Saleh, A.,Kelsall, E.,Morris, K.L.,Ragan, T.J.,Savva, C.G.,Chandru, A.,Millard, C.J.,Makarova, O.V.,Smith, C.J.,Roseman, A.M.,Fry, A.M.,Cowley, S.M.,Schwabe, J.W.R.; The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.; Nat Commun, 11:3252-3252, 2020; PubMed: 32591534; DOI: 10.1038/s41467-020-17078-8

実験手法

ELECTRON MICROSCOPY (4 Å)