6Z0E
HtrA1 inactive protease domain S328A with CARASIL mutation R274Q
Summary for 6Z0E
Entry DOI | 10.2210/pdb6z0e/pdb |
Descriptor | Serine protease HTRA1, CALCIUM ION (3 entities in total) |
Functional Keywords | hydrolase protease htra family carasil mutations trimerization, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 51314.66 |
Authors | Vetter, I.R.,Stege, P.,Ingendahl, L.,Ehrmann, M. (deposition date: 2020-05-08, release date: 2021-05-19, Last modification date: 2024-01-24) |
Primary citation | Ingendahl, L.,Beaufort, N.,Kuszner, M.,Vetter, I.R.,Stege, P.,Ruiz-Blanco, Y.B.,Bravo-Rodriguez, K.,Beuck, C.,Schillinger, J.,Rey, J.,Roberti, A.,Hagemeier, B.,Hu, X.-Y.,Clausen, T.,Sanchez-Garcia, E.,Schmuck, C.,Dichgans, M.,Ehrmann, M. Repair strategies addressing pathogenic protein conformations To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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