6Z0E
HtrA1 inactive protease domain S328A with CARASIL mutation R274Q
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine protease HTRA1 | polymer | 236 | 25617.3 | 2 | UniProt (Q92743) Pfam (PF13365) In PDB | Homo sapiens (Human) | High-temperature requirement A serine peptidase 1,L56,Serine protease 11 |
2 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
3 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A, B: 161 - 375 (UniProt: Q92743)
PDB | External Database | Details |
---|---|---|
Met 140 | - | initiating methionine |
Gly 141 | - | expression tag |
Ser 142 | - | expression tag |
Ser 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
His 146 | - | expression tag |
His 147 | - | expression tag |
His 148 | - | expression tag |
His 149 | - | expression tag |
Ser 150 | - | expression tag |
Ser 151 | - | expression tag |
Gly 152 | - | expression tag |
Leu 153 | - | expression tag |
Val 154 | - | expression tag |
Pro 155 | - | expression tag |
Arg 156 | - | expression tag |
Gly 157 | - | expression tag |
Ser 158 | - | expression tag |
His 159 | - | expression tag |
Met 160 | - | expression tag |
Gln 274 | Arg 274 | engineered mutation |
Ala 328 | Ser 328 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51234.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 80.2 | |
All* | Total formula weight | 51314.7 |