6YVO

Human OMPD-domain of UMPS in complex with the substrate OMP at 1.25 Angstroms resolution, 3.55 MGy exposure

Summary for 6YVO

Entry DOI	10.2210/pdb6yvo/pdb
Descriptor	Uridine 5'-monophosphate synthase, OROTIDINE-5'-MONOPHOSPHATE, URIDINE-5'-MONOPHOSPHATE, ... (6 entities in total)
Functional Keywords	ompd, omp, umps, orotidine 5'-monophosphate decarboxylase, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	29733.68
Authors	Tittmann, K.,Rindfleisch, S.,Krull, M. (deposition date: 2020-04-28, release date: 2022-02-23, Last modification date: 2024-10-16)
Primary citation	Rindfleisch, S.,Krull, M.,Uranga, J.,Schmidt, T.,Rabe von Pappenheim, F.,Kirck, L.L.,Balouri, A.,Schneider, T.,Chari, A.,Kluger, R.,Bourenkov, G.,Diederichsen, U.,Mata, R.A.,Tittmann, K. Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5:332-341, 2022 Cited by DOI: 10.1038/s41929-022-00771-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation