6YVM

Human OMPD-domain of UMPS in complex with the substrate OMP at 1.25 Angstroms resolution, 2.13 MGy exposure

Summary for 6YVM

• Entry DOI: 10.2210/pdb6yvm/pdb
• Descriptor: Uridine 5'-monophosphate synthase, OROTIDINE-5'-MONOPHOSPHATE, URIDINE-5'-MONOPHOSPHATE, ... (6 entities in total)
• Functional Keywords: ompd, omp, umps, orotidine 5'-monophosphate decarboxylase, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29733.68

Authors

Tittmann, K.,Rindfleisch, S.,Krull, M. (deposition date: 2020-04-28, release date: 2021-11-17, Last modification date: 2024-01-24)

• Primary citation: Rindfleisch, S.,Krull, M.,Uranga, J.,Schmidt, T.,Rabe von Pappenheim, F.,Kirck, L.L.,Balouri, A.,Schneider, T.,Chari, A.,Kluger, R.,Bourenkov, G.,Diederichsen, U.,Mata, R.A.,Tittmann, K.; Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis; Nat Catal, 5:332-341, 2022; DOI: 10.1038/s41929-022-00771-w

Experimental method

X-RAY DIFFRACTION (1.25 Å)