6YVH

CWC22-CWC27-EIF4A3 Complex

Summary for 6YVH

• Entry DOI: 10.2210/pdb6yvh/pdb
• Descriptor: Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog, Eukaryotic initiation factor 4A-III (3 entities in total)
• Functional Keywords: ejc helicase, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 237977.42

Authors

Basquin, J.,Busetto, V.,LeHir, H.,Conti, E. (deposition date: 2020-04-28, release date: 2020-05-13, Last modification date: 2024-01-24)

• Primary citation: Busetto, V.,Barbosa, I.,Basquin, J.,Marquenet, E.,Hocq, R.,Hennion, M.,Paternina, J.A.,Namane, A.,Conti, E.,Bensaude, O.,Le Hir, H.; Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.; Nucleic Acids Res., 48:5670-5683, 2020; PubMed: 32329775; DOI: 10.1093/nar/gkaa267

Experimental method

X-RAY DIFFRACTION (3.19 Å)