6YTU
Atomic-resolution structure of the coiled-coil dimerisation domain of human Arc
Summary for 6YTU
Entry DOI | 10.2210/pdb6ytu/pdb |
Descriptor | Activity-regulated cytoskeleton-associated protein, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | arc, oligomerisation, coiled coil, dimer, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 9205.96 |
Authors | Hallin, E.I.,Touma, C.,Bramham, C.R.,Kursula, P. (deposition date: 2020-04-24, release date: 2021-03-03, Last modification date: 2021-05-12) |
Primary citation | Eriksen, M.S.,Nikolaienko, O.,Hallin, E.I.,Grodem, S.,Bustad, H.J.,Flydal, M.I.,Merski, I.,Hosokawa, T.,Lascu, D.,Akerkar, S.,Cuellar, J.,Chambers, J.J.,O'Connell, R.,Muruganandam, G.,Loris, R.,Touma, C.,Kanhema, T.,Hayashi, Y.,Stratton, M.M.,Valpuesta, J.M.,Kursula, P.,Martinez, A.,Bramham, C.R. Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif. Febs J., 288:2930-2955, 2021 Cited by PubMed: 33175445DOI: 10.1111/febs.15618 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
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