6YRH

Transaldolase variant T30C/D211C from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate

6YRH の概要

• エントリーDOI: 10.2210/pdb6yrh/pdb
• 関連するPDBエントリー: 6YR3 6YRE
• 分子名称: Probable transaldolase, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: alpha-beta barrel, conformational selection, domain swapping, transferase, tim barrel, schiff base, large-scale motions, substrate binding, rate-determining product release
• 由来する生物種: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 124571.66

構造登録者

Sautner, V.,Lietzow, T.H.,Tittmann, K. (登録日: 2020-04-20, 公開日: 2021-05-12, 最終更新日: 2024-10-16)

• 主引用文献: Sautner, V.,Lietzow, T.H.,Klaus, M.,Funk, L.M.,Tittmann, K.; Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)