6YPK
Crystal Structure of CK2alpha with GTP bound
Summary for 6YPK
Entry DOI | 10.2210/pdb6ypk/pdb |
Descriptor | Casein kinase II subunit alpha, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | selective atp competitive inhibitors, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 39474.59 |
Authors | Brear, P.,Hyvonen, M. (deposition date: 2020-04-16, release date: 2020-07-15, Last modification date: 2024-01-24) |
Primary citation | Brear, P.,Ball, D.,Stott, K.,D'Arcy, S.,Hyvonen, M. Proposed Allosteric Inhibitors Bind to the ATP Site of CK2 alpha. J.Med.Chem., 63:12786-12798, 2020 Cited by PubMed: 33119282DOI: 10.1021/acs.jmedchem.0c01173 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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