6YOU

Crystal structure of the cAMP-dependent protein kinase A in complex with Pyrido[3,2-d]pyrimidin-4-amine (soaked)

6YOU の概要

• エントリーDOI: 10.2210/pdb6you/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, pyrido[3,2-d]pyrimidin-4-amine (3 entities in total)
• 機能のキーワード: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• 由来する生物種: Cricetulus griseus (Chinese hamster)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41339.89

構造登録者

Oebbeke, M.,Heine, A.,Klebe, G. (登録日: 2020-04-15, 公開日: 2021-04-28, 最終更新日: 2024-11-13)

• 主引用文献: Oebbeke, M.,Wienen-Schmidt, B.,Gerber, H.-D.,Heine, A.,Klebe, G.; Fragment based drug design - Small chemical changes of fragments effecting big changes in binding; To Be Published,

実験手法

X-RAY DIFFRACTION (1.73 Å)