6YL6
Cdk2(F80C)
Summary for 6YL6
Entry DOI | 10.2210/pdb6yl6/pdb |
Related | 6YL1 |
Descriptor | Cyclin-dependent kinase 2 (2 entities in total) |
Functional Keywords | covalent inhibitor, cysteine modification, kinase, allosteric inhibitor, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34311.85 |
Authors | Craven, G.,Morgan, R.M.L.,Mann, D.J. (deposition date: 2020-04-06, release date: 2020-07-22, Last modification date: 2024-01-24) |
Primary citation | Craven, G.B.,Affron, D.P.,Kosel, T.,Wong, T.L.M.,Jukes, Z.H.,Liu, C.T.,Morgan, R.M.L.,Armstrong, A.,Mann, D.J. Multiparameter Kinetic Analysis for Covalent Fragment Optimization by Using Quantitative Irreversible Tethering (qIT). Chembiochem, 21:3417-3422, 2020 Cited by PubMed: 32659037DOI: 10.1002/cbic.202000457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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