6YK6
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound (S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimidin-2,4-dione at resolution 1.47A
6YK6 の概要
エントリーDOI | 10.2210/pdb6yk6/pdb |
分子名称 | Glutamate receptor 2,Glutamate receptor 2, SULFATE ION, GLYCEROL, ... (7 entities in total) |
機能のキーワード | ionotropic glutamate receptor, glua2o ligand-binding domain, bicyclic pyrimidinedione analogue, membrane protein |
由来する生物種 | Rattus norvegicus (Norway rat) 詳細 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 30256.30 |
構造登録者 | |
主引用文献 | Frydenvang, K.,Pickering, D.S.,Kshirsagar, G.U.,Chemi, G.,Gemma, S.,Sprogoe, D.,Kærn, A.M.,Brogi, S.,Campiani, G.,Butini, S.,Kastrup, J.S. Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions. Acs Chem Neurosci, 11:1791-1800, 2020 Cited by PubMed: 32437601DOI: 10.1021/acschemneuro.0c00195 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.469 Å) |
構造検証レポート
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