6YK1

Crystal structure of mouse pyridoxal kinase in complex with ATP-gamma-S and artesunate

Summary for 6YK1

Entry DOI	10.2210/pdb6yk1/pdb
Descriptor	Pyridoxal kinase, GLYCEROL, TETRAETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywords	pdxk, plp, pl, vitamin b6, enzyme, artemisinin, artesunate, transferase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	145687.39
Authors	Kasaragod, V.B.,Schindelin, H. (deposition date: 2020-04-05, release date: 2021-04-14, Last modification date: 2024-01-24)
Primary citation	Kasaragod, V.B.,Pacios-Michelena, A.,Schaefer, N.,Zheng, F.,Bader, N.,Alzheimer, C.,Villmann, C.,Schindelin, H. Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proc.Natl.Acad.Sci.USA, 117:33235-33245, 2020 Cited by PubMed: 33318193 DOI: 10.1073/pnas.2008695117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation