6YHP
Solution NMR Structure of APP V44M mutant TMD
Summary for 6YHP
| Entry DOI | 10.2210/pdb6yhp/pdb |
| NMR Information | BMRB: 34509 |
| Descriptor | Amyloid-beta precursor protein V44M mutant (1 entity in total) |
| Functional Keywords | app, gamma secretase, transmembrane, membrane protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 3102.99 |
| Authors | Silber, M.,Muhle-Goll, C. (deposition date: 2020-03-30, release date: 2020-12-09, Last modification date: 2024-05-15) |
| Primary citation | Silber, M.,Hitzenberger, M.,Zacharias, M.,Muhle-Goll, C. Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme-Substrate Interactions of gamma-Secretase. Acs Chem Neurosci, 11:4426-4433, 2020 Cited by PubMed: 33232115DOI: 10.1021/acschemneuro.0c00640 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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