Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6YHO

Solution NMR Structure of APP G38P mutant TM

Summary for 6YHO
Entry DOI10.2210/pdb6yho/pdb
NMR InformationBMRB: 34508
DescriptorAmyloid-beta precursor protein G38P mutant (1 entity in total)
Functional Keywordsapp, gamma secretase, transmembrane, membrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight3110.99
Authors
Silber, M.,Muhle-Goll, C. (deposition date: 2020-03-30, release date: 2020-12-09, Last modification date: 2024-05-15)
Primary citationSilber, M.,Hitzenberger, M.,Zacharias, M.,Muhle-Goll, C.
Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme-Substrate Interactions of gamma-Secretase.
Acs Chem Neurosci, 11:4426-4433, 2020
Cited by
PubMed: 33232115
DOI: 10.1021/acschemneuro.0c00640
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon