6YGZ
tRNA Guanine Transglycosylase (TGT) labelled with 5-fluoro-tryptophan in co-crystallized complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Summary for 6YGZ
Entry DOI | 10.2210/pdb6ygz/pdb |
Related | 6YGR |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ... (4 entities in total) |
Functional Keywords | homodimer, 19f nmr, trna, tgt, transferase |
Biological source | Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 |
Total number of polymer chains | 1 |
Total formula weight | 43512.53 |
Authors | Nguyen, A.,Heine, A.,Klebe, G. (deposition date: 2020-03-28, release date: 2020-04-08, Last modification date: 2024-01-24) |
Primary citation | Nguyen, A.,Heine, A.,Klebe, G. Co-crystallization, 19F NMR and nanoESI-MS reveal dimer disturbing inhibitors and conformational changes at dimer contacts To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
Download full validation report