6YD9

Ecoli GyrB24 with inhibitor 16a

Summary for 6YD9

Entry DOI	10.2210/pdb6yd9/pdb
Descriptor	DNA gyrase subunit B, N-[6-(3-azanylpropanoylamino)-1,3-benzothiazol-2-yl]-3,4-bis(chloranyl)-5-methyl-1H-pyrrole-2-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	dna gyrase, topoisomerase iv, inhibitor, dna binding protein
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	24727.61
Authors	Barancokova, M.,Skok, Z.,Benek, O.,Cruz, C.D.,Tammela, P.,Tomasic, T.,Zidar, N.,Masic, L.P.,Zega, A.,Stevenson, C.E.M.,Mundy, J.,Lawson, D.M.,Maxwell, A.M.,Kikelj, D.,Ilas, J. (deposition date: 2020-03-20, release date: 2020-12-30, Last modification date: 2024-01-24)
Primary citation	Skok, Z.,Barancokova, M.,Benek, O.,Cruz, C.D.,Tammela, P.,Tomasic, T.,Zidar, N.,Masic, L.P.,Zega, A.,Stevenson, C.E.M.,Mundy, J.E.A.,Lawson, D.M.,Maxwell, A.,Kikelj, D.,Ilas, J. Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors. Acs Med.Chem.Lett., 11:2433-2440, 2020 Cited by PubMed: 33329764 DOI: 10.1021/acsmedchemlett.0c00416 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation