6YCI

Crystal structure of GcoA T296G bound to guaiacol

Summary for 6YCI

Entry DOI	10.2210/pdb6yci/pdb
Descriptor	Aromatic O-demethylase, cytochrome P450 subunit, PROTOPORPHYRIN IX CONTAINING FE, Guaiacol, ... (4 entities in total)
Functional Keywords	aromatic catabolism, cytochrome p450, lignin valorization, protein engineering, oxidoreductase
Biological source	Amycolatopsis sp. (strain ATCC 39116 / 75iv2)
Total number of polymer chains	1
Total formula weight	45995.18
Authors	Hinchen, D.J.,Mallinson, S.J.B.,Allen, M.D.,Ellis, E.S.,Beckham, G.T.,DuBois, J.L.,McGeehan, J.E. (deposition date: 2020-03-18, release date: 2021-02-17, Last modification date: 2024-01-24)
Primary citation	Ellis, E.S.,Hinchen, D.J.,Bleem, A.,Bu, L.,Mallinson, S.J.B.,Allen, M.D.,Streit, B.R.,Machovina, M.M.,Doolin, Q.V.,Michener, W.E.,Johnson, C.W.,Knott, B.C.,Beckham, G.T.,McGeehan, J.E.,DuBois, J.L. Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes. Jacs Au, 1:252-261, 2021 Cited by PubMed: 34467290 DOI: 10.1021/jacsau.0c00103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation