6Y8P
Crystal structure of SNAP-tag labeled with a benzyl-tetramethylrhodamine fluorophore
Summary for 6Y8P
Entry DOI | 10.2210/pdb6y8p/pdb |
Descriptor | O6-alkylguanine-DNA alkyltransferase mutant, ZINC ION, [9-[2-carboxy-5-[(4-methylphenyl)methylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium, ... (5 entities in total) |
Functional Keywords | snap-tag, self-labeling protein, tetramethylrhodamine, synthetic fluorophore, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19613.85 |
Authors | Gotthard, G.,Tanzer, T.,Johnsson, K.,Hiblot, J. (deposition date: 2020-03-05, release date: 2021-03-31, Last modification date: 2024-01-24) |
Primary citation | Wilhelm, J.,Kuhn, S.,Tarnawski, M.,Gotthard, G.,Tunnermann, J.,Tanzer, T.,Karpenko, J.,Mertes, N.,Xue, L.,Uhrig, U.,Reinstein, J.,Hiblot, J.,Johnsson, K. Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60:2560-2575, 2021 Cited by PubMed: 34339177DOI: 10.1021/acs.biochem.1c00258 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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