6Y2Y
The crystal structure of engineered cytochrome c peroxidase from Saccharomyces cerevisiae with Trp51 to S-Trp51 and Trp191Phe modifications
Summary for 6Y2Y
Entry DOI | 10.2210/pdb6y2y/pdb |
Descriptor | Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | peroxidase, heme, engineered, non-canonical amino acid, oxidoreductase |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Total number of polymer chains | 1 |
Total formula weight | 37587.45 |
Authors | Ortmayer, M.,Levy, C.,Green, A.P. (deposition date: 2020-02-17, release date: 2021-06-16, Last modification date: 2024-01-24) |
Primary citation | Ortmayer, M.,Hardy, F.J.,Quesne, M.G.,Fisher, K.,Levy, C.,Heyes, D.J.,Catlow, C.R.A.,de Visser, S.P.,Rigby, S.E.J.,Hay, S.,Green, A.P. A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase. Jacs Au, 1:913-918, 2021 Cited by PubMed: 34337604DOI: 10.1021/jacsau.1c00145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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