6Y1Z

Mouse serotonin 5HT3 receptor in complex with palonosetron

6Y1Z の概要

• エントリーDOI: 10.2210/pdb6y1z/pdb
• EMDBエントリー: 10673
• 分子名称: 5-hydroxytryptamine receptor 3A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: receptor, pentameric ligand-gated ion channel, antiemetic, transport protein
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 327858.32

構造登録者

Zarkadas, E.,Perot, J.,Nury, H. (登録日: 2020-02-14, 公開日: 2020-03-04, 最終更新日: 2022-09-14)

• 主引用文献: Zarkadas, E.,Zhang, H.,Cai, W.,Effantin, G.,Perot, J.,Neyton, J.,Chipot, C.,Schoehn, G.,Dehez, F.,Nury, H.; The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor.; Structure, 28:1131-1140.e4, 2020; PubMed: 32726573; DOI: 10.1016/j.str.2020.07.004

実験手法

ELECTRON MICROSCOPY (2.82 Å)