6XZY

crystal structure of human carbonic anhydrase I in complex with 4-(3-(2-((2-fluorobenzyl)amino)ethyl)ureido) benzenesulfonamide

Summary for 6XZY

Entry DOI	10.2210/pdb6xzy/pdb
Descriptor	Carbonic anhydrase 1, ZINC ION, 1-[2-[(2-fluorophenyl)methylamino]ethyl]-3-(3-sulfamoylphenyl)urea, ... (4 entities in total)
Functional Keywords	inhibitor, carbon dioxide, carbonic anhydrase, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	58676.01
Authors	Zanotti, G.,Majid, A.,Bozdag, M.,Angeli, A.,Carta, F.,Berto, P.,Supuran, C. (deposition date: 2020-02-05, release date: 2020-09-23, Last modification date: 2024-01-24)
Primary citation	Ali, M.,Bozdag, M.,Farooq, U.,Angeli, A.,Carta, F.,Berto, P.,Zanotti, G.,Supuran, C.T. Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 32272689 DOI: 10.3390/ijms21072560 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation