6XZ7

E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).

6XZ7 の概要

• エントリーDOI: 10.2210/pdb6xz7/pdb
• EMDBエントリー: 10655
• 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... (36 entities in total)
• 機能のキーワード: 50s ribosomal subunit, dirithromycin, antibiotics, cryo-em, ribosome
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 33
• 化学式量合計: 1404320.86

構造登録者

Pichkur, E.B.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L. (登録日: 2020-02-03, 公開日: 2020-07-22)

• 主引用文献: Pichkur, E.B.,Paleskava, A.,Tereshchenkov, A.G.,Kasatsky, P.,Komarova, E.S.,Shiriaev, D.I.,Bogdanov, A.A.,Dontsova, O.A.,Osterman, I.A.,Sergiev, P.V.,Polikanov, Y.S.,Myasnikov, A.G.,Konevega, A.L.; Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.; Rna, 26:715-723, 2020; PubMed: 32144191; DOI: 10.1261/rna.073817.119

実験手法

ELECTRON MICROSCOPY (2.1 Å)