6XYY

Update of ACHE FROM DROSOPHILA MELANOGASTER COMPLEX WITH TACRINE DERIVATIVE 9-(3-PHENYLMETHYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE

「1DX4」から置き換えられました

6XYY の概要

• エントリーDOI: 10.2210/pdb6xyy/pdb
• 関連するPDBエントリー: 6xys 6xyu
• 分子名称: Acetylcholinesterase, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROPANOIC ACID, ... (8 entities in total)
• 機能のキーワード: acetylcholinesterase, insect, inhibitor, complex, hydrolase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 66118.14

構造登録者

Nachon, F.,Sussman, J.L. (登録日: 2020-01-31, 公開日: 2020-03-18, 最終更新日: 2024-01-24)

• 主引用文献: Nachon, F.,Rosenberry, T.L.,Silman, I.,Sussman, J.L.; A Second Look at the Crystal Structures ofDrosophila melanogasterAcetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides.; Molecules, 25:-, 2020; PubMed: 32155891; DOI: 10.3390/molecules25051198

実験手法

X-RAY DIFFRACTION (2.7 Å)