6XYP

Multiple system atrophy Type II-1 alpha-synuclein filament

Summary for 6XYP

• Entry DOI: 10.2210/pdb6xyp/pdb
• EMDB information: 10651
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: multiple system atrophy, alpha-synuclein filament, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 144761.08

Authors

Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M. (deposition date: 2020-01-30, release date: 2020-02-12, Last modification date: 2024-05-22)

• Primary citation: Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M.; Structures of alpha-synuclein filaments from multiple system atrophy.; Nature, 585:464-469, 2020; PubMed: 32461689; DOI: 10.1038/s41586-020-2317-6

Experimental method

ELECTRON MICROSCOPY (3.29 Å)